WebThe c-Jun N-terminal kinase (JNK) pathway is one of the major signaling cassettes of the mitogen-activated protein kinase (MAPK) signaling pathway. It functions in the control of a number of cellular processes, … Webc-Jun is one of three Jun family proteins making up the activator protein-1 (AP-1) transcription factor group. c-Jun acts as a positive regulator of cell proliferation and can …
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WebAug 27, 1998 · Figure 1: Smad3/Smad4 and c-Jun–c-Fos cooperate to induce tra nscription from the AP-1 promoter. We measured the effects of Smads, c-Jun, and c-Fos on luciferase expression from AP-1 promoters ... WebProduct overview. c-Jun Transcription Factor Assay Kit (Colorimetric) (ab207195) is a high throughput assay to quantify AP-1 c-Jun activation in nuclear extracts. This assay combines a quick ELISA format with a sensitive and specific non-radioactive assay for transcription factor activation. A specific double stranded DNA sequence containing ... pic of shampoo bottle
C-JUN - Proteopedia, life in 3D
Webc-jun expression was found to be significantly higher in the peripheral blood cells of the lungs of COPD patients than healthy controls, suggesting excessive c-jun causes corticosteroid resistance. SMAP2 immunoprecipitated clathrin and AP-1 through a putative clathrin-binding domain and a CALM-binding domain, and SMAP2 mutants that did not ... WebDec 1, 2014 · c-Jun, a member of the basic region leucine zipper protein family of transcription factors, in combination with itself or other proteins such as c-Fos, forms the transcription factor activator protein 1 (AP-1). c-Jun protein consists of a C-terminal DNA-binding domain and an N-terminal transactivation domain. Webc-Jun is a member of the Jun family containing c-Jun, JunB, and JunD, and is a component of the transcription factor activator protein-1 (AP-1). AP-1 is composed of dimers of Fos, Jun, and ATF family members and binds to and activates transcription at TRE/AP-1 elements (reviewed in 1). Extracellular signals, including growth factors, chemokines ... pic of shadow from sonic