Human tenascin c
Webtenascin-C, which is the original “tenascin”; tenascin-R, with the “R” standing for “restric-tin”; tenascin-X, named after “human gene X”; and tenascin-W, named after its … Web1 Nov 2024 · Absolute levels of tenascin-C mRNA were quantified in a panel of stromal, myeloid and lymphocytic cells before stimulation. High basal levels were confirmed in human dermal fibroblasts (HDFs) and U-87MG glioma cells , with 1000-fold lower levels detected in immune cells.Monocytes, macrophages and dendritic cells contained higher …
Human tenascin c
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WebTenascin C regulates cancer cell glycolysis and tumor progression in prostate cancer. Tenascin-C Participates Pulmonary Injury Induced by Paraquat Through Regulating … Web10 Apr 2024 · A tenascin-C (TNC)+ fibroblast subpopulation emerges at the dermal-epidermal junction (DEJ) of psoriatic skin. ... Mercado identification of a neurite outgrowth …
WebTenascin-C (TN-C) is a large, hexameric, multi-domain extracellular matrix protein with restricted basal expression in adult tissues but that is transiently upregulated at sites of … WebThe human Tenascin C monomer is synthesized as a precursor with a 22 amino acid (aa) signal sequence and a 2179 aa mature chain. The mature chain consists of a coiled-coil …
WebSpecies Reactivity Human Specificity Detects human Tenascin R in direct ELISAs and Western blots. In direct ELISAs and Western blots, less than 1% cross-reactivity with recombinant human Tenascin C is observed. Source Polyclonal Goat IgG Purification Antigen Affinity-purified Immunogen WebGenetic variation at the human tenascin-C gene locus is associated with 6-fold increase in risk of Achilles tendon injury,16 non-syndromic hearing loss,17 and increased risk of …
Web24 Aug 2024 · Tenascin C in colorectal cancer stroma is a predictive marker for liver metastasis and is a potent target of miR-198 as identified by microRNA analysis British Journal of Cancer Tumour stroma...
Web22 Aug 2006 · Human monoclonal antibodies to domain C of tenascin-C selectively target solid tumors in vivo Protein Engineering, Design and Selection Oxford Academic Abstract. We had previously reported that splice isoforms of tenascin-C containing the extra-domain C are virtually absent in normal adult tissues but are highl Skip to Main Content set up a nonprofit organization freeWeb3 Jun 2016 · The Human Tenascin-C Large (FN III-C) Assay Kits (IBL, Gunma, Japan) used detects the alternately spliced isoform of tenascin-C that includes the FN III-C domain. Results were calculated from ... the toilets smokingWeb20 Aug 2024 · Tenascin-C (TNC) is an extracellular matrix (ECM) glycoprotein that plays an important role in cell proliferation, migration, and tumour invasion in various cancers. … set up a not for profitWebTenascin-C deposition is a useful histological marker of interstitial remodeling in animal models [103] and in human patients with ischemic cardiomyopathy [104]. Although … set up a not for profit ukWeb20 Aug 2024 · Tenascin-C (TNC) is an extracellular matrix (ECM) glycoprotein that plays an important role in cell proliferation, migration, and tumour invasion in various cancers. TNC is one of the main protein overexpressed in breast cancer, indicating a role for this ECM molecule in cancer pathology. the toilet song by the wigglesWeb30 Nov 2016 · Tenascin-C is the best studied of the tenascins and is prominently expressed in the embryo at sites of cell migration, epithelial-mesenchymal interactions, and in developing connective tissue. In the adult, tenascin-C is found at the edges of healing wounds, in many stem cell niches, at sites of inflammation, and in the stroma of solid … set up another userWeb18 Apr 2013 · Tenascin C (TNC) is a complex multifunctional extracellular matrix (ECM) glycoprotein forming a disulfide-bonded hexabrachion. The monomeric unit consists of four major domains ( Figure 1, A) [1], [2]. The N-terminal domain mediates hexamerization by forming a coiled structure with interchain disulfide bonds. thetoiletstool.com