Ototoxicity and cancer therapy
WebNov 1, 2024 · Greater severity is associated with younger age, combined therapy with cisplatin and the irradiation dose, with a maximum dose of 35 Gy recommended for … WebThere are more than 200 known ototoxic medications (prescription and over-the-counter) on the market today. These include medicines used to treat serious infections, cancer, and …
Ototoxicity and cancer therapy
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WebApr 7, 2024 · EMA Recommends Granting a Paediatric-Use Marketing Authorisation for Sodium Thiosulfate. It is indicated for the prevention of ototoxicity induced by cisplatin in paediatric patients with localised, non-metastatic, solid tumours. Date: 07 Apr 2024. Topics: Anticancer agents & Biologic therapy; Cancer in Special Situations / Population ... WebMar 31, 2024 · After 5 years from the end of the treatment, the number of patients with exhibiting ototoxicity was 31 (58.5%); the factors that influenced the onset/progression of the damage were having undergone radiotherapy (HR 1.23; p < 0.01) and having received therapy with aminoglycosides (HR 1.27; p < 0.01).
WebABSTRACT. Background: The aim of this study is to evaluate the current state of ototoxicity monitoring for patients receiving cisplatin chemotherapy in an academic medical center with particular attention to how closely monitoring adheres to national ototoxicity guidelines.. Methods: Case series including retrospective medical records review of patients (age > … WebAug 9, 2024 · The researchers hypothesised that the covalent bonding of STS to cisplatin may attenuate the chemotherapy agent’s anticancer activity as well as reducing …
WebMar 15, 2024 · Cisplatin is a bedrock of cancer management and one of the most used chemotherapeutic agents in the treatment of germ cell, lung, bladder, ovarian, and head … WebTo date, there have been a small number of reports of patients with isolated hearing loss after receiving ICI for cancer therapy.6–8 In two reports of patients treated for melanoma, …
WebCarboplatin and Oxaloplatin are less ototoxic, but still have ototoxic potential. Cisplatin is used in the treatment of solid tumors of head, neck, lung, ovary, testicle and bladder …
WebCitation 3–5 As a result, docetaxel-induced ototoxicity has not been reported in the literature. Therefore, no warning is included regarding this side effect in the drug … lei cha one northWebOtotoxicity is a medication side effect involving damage to your inner ear. It can cause symptoms like ringing in your ears, hearing loss and balance problems. Healthcare … leicester x newcastle palpiteWebOtotoxicity is a well-established toxicity associated with a subgroup of antineoplastic therapies that includes platinum chemotherapy, radiation or surgery involving the ear and … leicha shaver emailWebNov 6, 2024 · Ototoxicity (i.e., toxic damage to the ear) is a side effect of many drugs that are used in cancer treatment, including anticancer drugs and co-medication such as … leichardt active carrotWebObjectives: Cisplatin-induced ototoxicity is a common permanent consequence of curative chemoradiation for locally advanced head and neck squamous cell carcinoma (HNSCC). Predictors of ototoxicity in HNSCC were examined. Materials and methods: In this prospective, observational cohort study, 206 adult HNSCC patients underwent … leicester youtubersWebCancer Therapy Evaluation Program, Common Terminology Criteria for Adverse Events, Version 3.0, DCTD, NCI, NIH, DHHS ... 1 Drug-induced ototoxicity should be distinguished … leicha shaver apiWebFeb 9, 2016 · Ototoxicity is a well-established toxicity associated with a subgroup of antineoplastic therapies that includes platinum chemotherapy, radiation or surgery … leicf heart defect