Toxicities of 166holmium-chitosan in mice
WebChitosan oligomers did not induce morphologic sperm abnormalities in male mice following oral gavage daily for 5 days with up to 5,000 mg/kg. 21. … WebApr 1, 2013 · The toxicity of chitosan nanoparticles needs to be evaluated in embryo development aspects because extensive research into their biomedical applications was based largely on the biodegradable and biocompatible profile of chitosan. ... The mice were housed in wire cages at 22 ± 1°C under a 12L:12D cycle with 70% humidity and fed ad …
Toxicities of 166holmium-chitosan in mice
Did you know?
WebJan 31, 2010 · No oral toxicity was found in mice treated with 100 mg/kg chitosan nanoparticles (80 kDa, 80% DD) [81]. There was slight toxicity at high dose observed in … WebDec 10, 2024 · This study was conducted to evaluate the subacute toxicity effect of Chitosan-alginate coated microparticle of Garcinia mangostana Linn extract’s oral administration. Fifty BALB/c mice were...
WebMay 11, 2024 · Disc diffusion method was used to test for activity against Escherichia coli ( E. coli) and Staphylococcus aureus ( S. aureus) with Fosbac as the positive control. Acute toxicity in mice through oral administration of the nanoparticles solution at … WebMar 1, 1998 · In this study, 166Ho was complexed to chitosan (Chit) which decreases the distribution of Ho into other tissues when applied intrahepatically. To investigate the …
WebThe level of radioactivity in blood, urinary and faecal excretion, and radioactivity distribution were examined. To determine the effect of chitosan in DW-166HC, 166Ho nitrate alone [0.1875 mg of Ho(NO3)3.5H2O] was administered into the prostate of male rats, and radioactivity distribution was examined using whole-body autoradiography. WebTo investigate the single dose toxicity, mice were administered intravenously with 1 mCi/kg body weight of 166Ho-Chit (DW-166HC), Chit or nothing. Organ weights, hematological …
WebDec 1, 2005 · The fate of 166Ho-chitosan complex, a radiopharmaceutical drug for cancer therapy, was determined by studying its absorption, distribution and excretion in rats and …
WebApr 1, 2024 · To evaluate the biological safety of chitosan nanoparticles, chronic toxicity study was conducted in Swiss albino mice. Briefly, the animals were divided into two groups of 5 each. Animals of group I were given corn oil in normal diet on alternative days and those of group II were fed with 0.5% dosage of void nanoparticles in water on ... health benefits of bitter melon extractWebMar 1, 1998 · In this study, 166Ho was complexed to chitosan (Chit) which decreases the distribution of Ho into other tissues when applied intrahepatically. To investigate the single dose toxicity, mice were administered intravenously with 1 mCi/kg body weight of 166Ho … health benefits of black beansWebSep 20, 2024 · This study assessed the protective effects of selenium-chitosan (SC) against antioxidant and immune function-related damage induced by zearalenone (ZEN) in mice. … health benefits of bitter leaf teaWebAbbreviation / Long Form : 166Ho / 166Holmium [Related PubMed/MEDLINE] Total Number of Papers: 1 [Entries Per Page] per page Page Control Page: of : Abbreviation: 166Ho (>> Co-occurring Abbreviation) Long Form: ... Toxicities of 166Holmium-chitosan in mice. health benefits of bitter melon leavesWeb166 Holmium-Chitosan complex, in which chitosan is chelated with 166 Holmium, was developed as a radiopharmaceutical for cancer therapy. We have conducted a pilot study to evaluate the clinical efficacy of transarterial administration of 166 Holmium-Chitosan complex in patients with a single and small (< 3 cm) hepatocellular carcinoma. 166 golf phoneticsWebApr 13, 2024 · The chitosan-coated nanoemulsions with TMZ showed the expected physicochemical characteristics and demonstrated safety and efficacy, reducing around 70% the tumor size compared to control mice, and presenting a tendency in mitotic index reduction, becoming an interesting approach to treat melanoma brain metastasis. ... To … health benefits of black beans for womenWebIn vivo toxicity evaluation of tumor targeted glycol chitosan nanoparticles in healthy mice: repeated high-dose of glycol chitosan nanoparticles potentially induce cardiotoxicity Authors Yoon H.Y.; Lee S.; Kim K.; Chang H.; Yhee J.Y.; Jeon S.; Shim M.K. Ewha Authors 김광명 SCOPUS Author ID 김광명 Issue Date 2024 Journal Title health benefits of bitter leaf plant